PURPOSE: To evaluate the visual acuity outcomes and defocus curve of an enhanced monofocal IOL implanted bilaterally in cataract patients.

METHODS: This ambispective, single-arm, multicenter study included 82 subjects who had undergone bilateral implantation of an enhanced monofocal IOL, enVista Aspire (EA). EA is an IOL with intermediate optimized optics that provides a continuous depth of focus from distance to intermediate. The IOL uses an optical modification of the posterior aspheric surface to create a small continuous increase in IOL power within the central 1.5 mm diameter to slightly extend the depth of focus. Outcome measures included monocular (first implanted eye) and binocular visual acuities at distance, intermediate, and near, and the binocular defocus curve at least 2 months after IOL implantation in the second eye.

RESULTS: Postoperatively, mean logMAR UDVA and CDVA in the first implanted eyes were 0.12 ± 0.14 and -0.01± 0.09, respectively. Mean postoperative MRSE was -0.38 ± 0.47 D. Mean monocular logMAR UIVA and UNVA were 0.21± 0.15 and 0.42 ± 0.17; 58.5% of eyes achieved UIVA 20/32 or better, and 34.1% of eyes achieved UNVA 20/40 or better. The mean binocular logMAR DCIVA and DCNVA were 0.21 ± 0.13 and 0.39 ± 0.14, respectively, with 65.9% of patients achieving DCIVA 20/32 or better, and 35.4% achieving DCNVA 20/40 or better. Defocus curve showed 20/32 or better visual acuity for a defocus range of ~ +1.00 D to -1.25 D.

CONCLUSION: The implantation of an enhanced monofocal IOL resulted in improved depth of focus, yielding good visual acuity outcomes for intermediate vision with nearly 2/3 rd of the subjects achieving distance corrected intermediate visual acuity of 20/32 or better, postoperatively.